Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer

Vγ9Vδ2 T cells are known to be efficient anti-tumor effectors activated through phosphoantigens (PAg) that are naturally expressed by tumor cells or induced by amino bisphosphonates treatment. This PAg-activation which is TCR and butyrophilin BTN3A dependent can be modulated by NKG2D ligands, immune...

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Pubblicato in:Front Immunol
Autori principali: Laplagne, Chloé, Meddour, Sarah, Figarol, Sarah, Michelas, Marie, Calvayrac, Olivier, Favre, Gilles, Laurent, Camille, Fournié, Jean-Jacques, Cabantous, Stéphanie, Poupot, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358576/
https://ncbi.nlm.nih.gov/pubmed/32733462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01396
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