Specific requirements for Vγ9Vδ2 T cell stimulation by a natural adenylated phosphoantigen

Human Vγ9Vδ2 T lymphocytes recognize phosphorylated alkyl antigens. Isopentenyl pyrophosphate (IPP) was previously proposed as the main antigen responsible for Vγ9Vδ2 T cell activation by cancer cells. However ApppI, a metabolite in which the isopentenyl moiety is linked to ATP, was reported in cell...

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Main Authors: Vantourout, Pierre, Mookerjee-Basu, Jayati, Rolland, Corinne, Pont, Frédéric, Martin, Hélène, Davrinche, Christian, Martinez, Laurent O., Perret, Bertrand, Collet, Xavier, Périgaud, Christian, Peyrottes, Suzanne, Champagne, Eric
Format: Artigo
Language:Inglês
Published: American Association of Immunologists 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809082/
https://ncbi.nlm.nih.gov/pubmed/19710470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901085
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