Sterically Induced Conformational Restriction: Discovery and Preclinical Evaluation of Novel Pyrrolo[3, 2-d]pyrimidines as Microtubule Targeting Agents

פריטים דומים

• Novel Water Soluble, Substituted Pyrrolo[3,2-d]pyrimidines: Design, Synthesis and Biological Evaluation as Antitubulin Antitumor Agents
  מאת: Gangjee, Aleem, et al.
  יצא לאור: (2012)
• Discovery and Preclinical Evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as Single Agents with Microtubule Targeting Effects along with Triple-acting Angiokinase Inhibition as Antitumor Agents
  מאת: Pavana, Roheeth Kumar, et al.
  יצא לאור: (2016)
• The 3-D Conformational Shape of N-Naphthyl -cyclopenta[d]pyrimidines Affects Their Potency as Microtubule Targeting Agents and Their Antitumor Activity
  מאת: Xiang, Weiguo, et al.
  יצא לאור: (2020)
• Eribulin Mesylate: Mechanism of Action of a Unique Microtubule Targeting Agent
  מאת: Dybdal-Hargreaves, Nicholas F., et al.
  יצא לאור: (2015)
• Structure based drug design and in vitro metabolism study: discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
  מאת: Xiang, Weiguo, et al.
  יצא לאור: (2018)