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Eribulin Mesylate: Mechanism of Action of a Unique Microtubule Targeting Agent

Eribulin mesylate (eribulin), an analog of the marine natural product halichondrin B, is a microtubule-depolymerizing drug that has utility in the treatment of patients with breast cancer. Clinical trial results have demonstrated that eribulin treatment provides a survival advantage to patients with...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Dybdal-Hargreaves, Nicholas F., Risinger, April L., Mooberry, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812567/
https://ncbi.nlm.nih.gov/pubmed/25838395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3252
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