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Breast Cancer Cell Lines Exhibit Differential Sensitivities to Microtubule-targeting Drugs Independent of Doubling Time

BACKGROUND: Microtubule-targeting agents (MTAs) are a mainstay in breast cancer treatment, yet patient responses differ. The underlying mechanisms of these differences are unknown. While MTAs are mitotic inhibitors, recent evidence highlights that non-mitotic effects of these drugs can contribute to...

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Publié dans:Anticancer Res
Auteurs principaux: RISINGER, APRIL L., DYBDAL-HARGREAVES, NICHOLAS F., MOOBERRY, SUSAN L.
Format: Artigo
Langue:Inglês
Publié: 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812601/
https://ncbi.nlm.nih.gov/pubmed/26504006
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