Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea

Triple-negative breast cancers (TNBC) are aggressive and heterogeneous cancers that lack targeted therapies. We implemented a screening program to identify new leads for subgroups of TNBC using diverse cell lines with different molecular drivers. Through this program, we identified an extract from C...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Pederson, Petra J., Cai, Shengxin, Carver, Chase, Powell, Douglas R., Risinger, April L., Grkovic, Tanja, O’Keefe, Barry R., Mooberry, Susan L., Cichewicz, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540184/
https://ncbi.nlm.nih.gov/pubmed/32649211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.0c00423
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