Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

Por Cichewicz, Robert H.
Publicado em 2009

Chlorinated Polyketide Obtained from a Daldinia sp. Treated with the Epigenetic Modifier Suberoylanilide Hydroxamic Acid

Por Du, Lin, King, Jarrod B., Cichewicz, Robert H.
Publicado no J Nat Prod (2014)

Chemoreactive Natural Products Afford Resistance against Disparate Antibiotics and Toxins()

Por Du, Lin, You, Jianlan, Nicholas, Kenneth M., Cichewicz, Robert H.
Publicado no Angew Chem Int Ed Engl (2016)

Production of Cytotoxic Glidobactins/Luminmycins by Photorhabdus asymbiotica in Liquid Media and Live Crickets

Por Theodore, Christine M., King, Jarrod B., You, Jianlan, Cichewicz, Robert H.
Publicado em 2012

Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer

Por Robles, Andrew J., Cai, Shengxin, Cichewicz, Robert H., Mooberry, Susan L.
Publicado no Breast Cancer Res Treat (2016)

Maximiscin Induces DNA damage, Activates DNA Damage Response Pathways and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer

Por Robles, Andrew J., Du, Lin, Cichewicz, Robert H., Mooberry, Susan L.
Publicado no J Nat Prod (2016)

Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice

Por Joyner, P. Matthew, Matheke, Ronni M., Smith, Lindsey M., Cichewicz, Robert H.
Publicado em 2010

Reappraising the structures and distribution of metabolites from black aspergilli containing uncommon 2-benzyl-4H-pyran-4-one and 2-benzylpyridin-4(1H)-one systems

Por Henrikson, Jon C., Ellis, Trevor K., King, Jarrod B., Cichewicz, Robert H.
Publicado em 2011

Waikialoid A Suppresses Hyphal Morphogenesis and Inhibits Biofilm Development in Pathogenic Candida albicans

Por Wang, Xiaoru, You, Jianlan, King, Jarrod B., Powell, Douglas R., Cichewicz, Robert H.
Publicado em 2012

Small-molecule suppressors of Candida albicans biofilm formation synergistically enhance the antifungal activity of amphotericin B against clinical Candida isolates

Por You, Jianlan, Du, Lin, King, Jarrod B., Hall, Brian E., Cichewicz, Robert H.
Publicado em 2013

Bioactive Sulfur-Containing Sulochrin Dimers and Other Metabolites from an Alternaria sp. Isolate from a Hawaiian Soil Sample

Por Cai, Shengxin, King, Jarrod B., Du, Lin, Powell, Douglas R., Cichewicz, Robert H.
Publicado em 2014

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition

Por Joyner, P. Matthew, Liu, Jinman, Zhang, Zhijun, Merritt, Justin, Qi, Fengxia, Cichewicz, Robert H.
Publicado em 2010

Cytotoxic Dimeric Epipolythiodiketopiperazines from the Ascomycetous Fungus Preussia typharum

Por Du, Lin, Robles, Andrew J., King, Jarrod B., Mooberry, Susan L., Cichewicz, Robert H.
Publicado em 2014

A Potent HDAC Inhibitor, 1-Alaninechlamydocin, from a Tolypocladium sp. Induces G2/M Cell Cycle Arrest and Apoptosis in MIA PaCa-2 Cells

Por Du, Lin, Risinger, April L., King, Jarrod B., Powell, Douglas R., Cichewicz, Robert H.
Publicado em 2014

Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission

Por Niu, Guodong, Wang, Bin, Zhang, Genwei, King, Jarrod B., Cichewicz, Robert H., Li, Jun
Publicado no Sci Rep (2015)

Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics

Por Lee, Jin Woo, Collins, Jennifer E., Wendt, Karen L., Chakrabarti, Debopam, Cichewicz, Robert H.
Publicado no J Nat Prod (2021)

Secondary Metabolites from an Algicolous Aspergillus versicolor Strain

Por Miao, Feng-Ping, Li, Xiao-Dong, Liu, Xiang-Hong, Cichewicz, Robert H., Ji, Nai-Yun
Publicado em 2012

Spiro Fused Diterpene-Indole Alkaloids from a Creek-Bottom-Derived Aspergillus terreus

Por Cai, Shengxin, Du, Lin, Gerea, Alexandra L., King, Jarrod B., You, Jianlan, Cichewicz, Robert H.
Publicado em 2013

Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Trip...

Por Kil, Yun-Seo, Risinger, April L., Petersen, Cora L., Mooberry, Susan L., Cichewicz, Robert H.
Publicado no J Nat Prod (2020)

Growth Inhibition of Colon Cancer and Melanoma Cells by Versiol Derivatives from a Paraconiothyrium sp.

Por Cho, Namki, Ransom, Tanya T., Sigmund, Janet, Tran, Trong, Cichewicz, Robert H., Goetz, Michael, Beutler, John A.
Publicado no J Nat Prod (2017)