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Small-molecule suppressors of Candida albicans biofilm formation synergistically enhance the antifungal activity of amphotericin B against clinical Candida isolates

A new class of fungal biofilm inhibitors represented by shearinines D (3) and E (4) were obtained from a Penicillium sp. isolate. The inhibitory activities of 3 and 4 were characterized using a new imaging flow-cytometer technique, which enabled the rapid phenotypic analysis of Candida albicans cell...

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Autors principals: You, Jianlan, Du, Lin, King, Jarrod B., Hall, Brian E., Cichewicz, Robert H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631451/
https://ncbi.nlm.nih.gov/pubmed/23387427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400009f
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