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CryoEM for small molecules discovery, design, understanding and application.
We present a perspective of our view of the application of cryo electron microscopy (cryoEM) to structure based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryoEM, and the challenges that need to be overcome for this technique to reach its full pote...
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| Опубликовано в: : | Cell Chem Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239957/ https://ncbi.nlm.nih.gov/pubmed/30100349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.07.006 |
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