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CryoEM for small molecules discovery, design, understanding and application.

We present a perspective of our view of the application of cryo electron microscopy (cryoEM) to structure based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryoEM, and the challenges that need to be overcome for this technique to reach its full pote...

詳細記述

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書誌詳細
出版年:Cell Chem Biol
主要な著者: Scapin, Giovanna, Potter, Clinton S., Carragher, Bridget
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239957/
https://ncbi.nlm.nih.gov/pubmed/30100349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.07.006
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