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CryoEM for small molecules discovery, design, understanding and application.

We present a perspective of our view of the application of cryo electron microscopy (cryoEM) to structure based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryoEM, and the challenges that need to be overcome for this technique to reach its full pote...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Scapin, Giovanna, Potter, Clinton S., Carragher, Bridget
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239957/
https://ncbi.nlm.nih.gov/pubmed/30100349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.07.006
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