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CryoEM for small molecules discovery, design, understanding and application.

We present a perspective of our view of the application of cryo electron microscopy (cryoEM) to structure based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryoEM, and the challenges that need to be overcome for this technique to reach its full pote...

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Vydáno v:Cell Chem Biol
Hlavní autoři: Scapin, Giovanna, Potter, Clinton S., Carragher, Bridget
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239957/
https://ncbi.nlm.nih.gov/pubmed/30100349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.07.006
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