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CryoEM for small molecules discovery, design, understanding and application.

We present a perspective of our view of the application of cryo electron microscopy (cryoEM) to structure based drug design (SBDD). We discuss the basic needs and requirements for SBDD, the current state of cryoEM, and the challenges that need to be overcome for this technique to reach its full pote...

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Bibliografski detalji
Izdano u:Cell Chem Biol
Glavni autori: Scapin, Giovanna, Potter, Clinton S., Carragher, Bridget
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239957/
https://ncbi.nlm.nih.gov/pubmed/30100349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.07.006
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