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CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization
Programmable control of spatial genome organization is a powerful approach for studying how nuclear structure affects gene regulation and cellular function. Here, we develop a versatile CRISPR-genome organization (CRISPR-GO) system that can efficiently control the spatial positioning of genomic loci...
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| Vydáno v: | Cell |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239909/ https://ncbi.nlm.nih.gov/pubmed/30318144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.013 |
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