Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells

Repurposed CRISPR-Cas molecules provide a useful tool set for broad applications of genomic editing and regulation of gene expression in prokaryotes and eukaryotes. Recent discovery of phage-derived proteins, anti-CRISPRs, which serve to abrogate natural CRISPR anti-phage activity, potentially expan...

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Publicado no:Nat Commun
Main Authors: Nakamura, Muneaki, Srinivasan, Prashanth, Chavez, Michael, Carter, Matthew A., Dominguez, Antonia A., La Russa, Marie, Lau, Matthew B., Abbott, Timothy R., Xu, Xiaoshu, Zhao, Dehua, Gao, Yuchen, Kipniss, Nathan H., Smolke, Christina D., Bondy-Denomy, Joseph, Qi, Lei S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331597/
https://ncbi.nlm.nih.gov/pubmed/30643127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08158-x
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