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Methods and applications of CRISPR-mediated base editing in eukaryotic genomes

The past several years have seen an explosion in development of applications for the CRISPR-Cas9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of DNA and chromatin-modifying enzymes. While homology-directed repair (HDR) coupled with Cas9 nuclease clea...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Hess, Gaelen T., Tycko, Josh, Yao, David, Bassik, Michael C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997582/
https://ncbi.nlm.nih.gov/pubmed/28985508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.029
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