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Methods and applications of CRISPR-mediated base editing in eukaryotic genomes
The past several years have seen an explosion in development of applications for the CRISPR-Cas9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of DNA and chromatin-modifying enzymes. While homology-directed repair (HDR) coupled with Cas9 nuclease clea...
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| Publicat a: | Mol Cell |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997582/ https://ncbi.nlm.nih.gov/pubmed/28985508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.029 |
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