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Methods and applications of CRISPR-mediated base editing in eukaryotic genomes
The past several years have seen an explosion in development of applications for the CRISPR-Cas9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of DNA and chromatin-modifying enzymes. While homology-directed repair (HDR) coupled with Cas9 nuclease clea...
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| Опубликовано в: : | Mol Cell |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997582/ https://ncbi.nlm.nih.gov/pubmed/28985508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.029 |
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