CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization

Programmable control of spatial genome organization is a powerful approach for studying how nuclear structure affects gene regulation and cellular function. Here, we develop a versatile CRISPR-genome organization (CRISPR-GO) system that can efficiently control the spatial positioning of genomic loci...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Wang, Haifeng, Xu, Xiaoshu, Nguyen, Cindy M., Liu, Yanxia, Gao, Yuchen, Lin, Xueqiu, Daley, Timothy, Kipniss, Nathan H., Russa, Marie La, Qi, Lei S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239909/
https://ncbi.nlm.nih.gov/pubmed/30318144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.013
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