CRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens

Pooled CRISPR screens allow researchers to interrogate genetic causes of complex phenotypes at the genome-wide scale and promise higher specificity and sensitivity compared to competing technologies. Unfortunately, two problems exist, particularly for CRISPRi/a screens: variability in guide efficien...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Daley, Timothy P., Lin, Zhixiang, Lin, Xueqiu, Liu, Yanxia, Wong, Wing Hung, Qi, Lei S.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176515/
https://ncbi.nlm.nih.gov/pubmed/30296940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1538-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker