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A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and variants has led to significant mortality. We recently reported that an RNA-targeting CRISPR-Cas13 system, called prophylactic antiviral CRISPR in human cells (PAC-MAN), offere...

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Detalhes bibliográficos
Publicado no:Cell Rep Med
Main Authors: Lin, Xueqiu, Liu, Yanxia, Chemparathy, Augustine, Pande, Tara, La Russa, Marie, Qi, Lei S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985958/
https://ncbi.nlm.nih.gov/pubmed/33778788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100245
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