Role of EphB3 receptor in mediating head and neck tumor growth, cell migration, and response to PI3K inhibitor

Eph proteins have emerged as critical drivers affecting tumor growth and progression in human malignancies. Our TCGA data analysis showed that EphB3, a receptor tyrosine kinase, is frequently co-amplified with PIK3CA in head and neck squamous cell carcinoma (HNSCC). We therefore hypothesized that Ep...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Ther
Asıl Yazarlar: Bhatia, Shilpa, Griego, Anastacia, Lennon, Shelby, Oweida, Ayman, Sharma, Jaspreet, Rohmer, Christina, Uyanga, Nomin, Bukkapatnam, Sanjana, Court, Benjamin Van, Raben, David, Young, Christian, Heasley, Lynn, Karam, Sana D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238629/
https://ncbi.nlm.nih.gov/pubmed/29970482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1163
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