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Role of EphB3 receptor in mediating head and neck tumor growth, cell migration, and response to PI3K inhibitor

Eph proteins have emerged as critical drivers affecting tumor growth and progression in human malignancies. Our TCGA data analysis showed that EphB3, a receptor tyrosine kinase, is frequently co-amplified with PIK3CA in head and neck squamous cell carcinoma (HNSCC). We therefore hypothesized that Ep...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer Ther
Hoofdauteurs: Bhatia, Shilpa, Griego, Anastacia, Lennon, Shelby, Oweida, Ayman, Sharma, Jaspreet, Rohmer, Christina, Uyanga, Nomin, Bukkapatnam, Sanjana, Court, Benjamin Van, Raben, David, Young, Christian, Heasley, Lynn, Karam, Sana D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238629/
https://ncbi.nlm.nih.gov/pubmed/29970482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1163
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