Inhibition of EphB4-ephrin-B2 signaling reprograms the tumor immune microenvironment in head and neck cancers

Identifying targets present in the tumor microenvironment that contribute to immune evasion has become an important area of research. In the current study, we identified EphB4-ephrin-B2 signaling as a regulator of both innate and adaptive components of the immune system. EphB4 belongs to receptor ty...

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Udgivet i:Cancer Res
Main Authors: Bhatia, Shilpa, Oweida, Ayman, Lennon, Shelby, Darragh, Laurel B., Milner, Dallin, Phan, Andy V., Mueller, Adam C., Van Court, Benjamin, Raben, David, Serkova, Natalie J., Wang, Xiao-Jing, Jimeno, Antonio, Clambey, Eric T., Pasquale, Elena B., Karam, Sana D.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522285/
https://ncbi.nlm.nih.gov/pubmed/30894369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3257
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