Inhibition of EphB4-ephrin-B2 signaling reprograms the tumor immune microenvironment in head and neck cancers

Identifying targets present in the tumor microenvironment that contribute to immune evasion has become an important area of research. In the current study, we identified EphB4-ephrin-B2 signaling as a regulator of both innate and adaptive components of the immune system. EphB4 belongs to receptor ty...

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Vydáno v:Cancer Res
Hlavní autoři: Bhatia, Shilpa, Oweida, Ayman, Lennon, Shelby, Darragh, Laurel B., Milner, Dallin, Phan, Andy V., Mueller, Adam C., Van Court, Benjamin, Raben, David, Serkova, Natalie J., Wang, Xiao-Jing, Jimeno, Antonio, Clambey, Eric T., Pasquale, Elena B., Karam, Sana D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522285/
https://ncbi.nlm.nih.gov/pubmed/30894369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3257
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