Pancreatic tumor microenvironment modulation by EphB4-ephrinB2 inhibition and radiation combination

PURPOSE: A driving factor in pancreatic ductal adenocarcinoma (PDAC) treatment resistance is the tumor microenvironment, which is highly immunosuppressive. One potent immunological adjuvant is radiation therapy. Radiation, however, has also been shown to induce immunosuppressive factors, which can c...

詳細記述

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Lennon, Shelby, Oweida, Ayman, Milner, Dallin, Phan, Andy V., Bhatia, Shilpa, Van Court, Benjamin, Darragh, Laurel, Mueller, Adam C., Raben, David, Martínez-Torrecuadrada, Jorge L., Pitts, Todd M., Somerset, Hilary, Jordan, Kimberly R., Hansen, Kirk C., Williams, Jason, Messersmith, Wells A., Schulick, Richard D., Owens, Philip, Goodman, Karyn A., Karam, Sana D.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548606/
https://ncbi.nlm.nih.gov/pubmed/30944125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2811
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