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LIN28 selectively modulates a subclass of let-7 microRNAs
LIN28 is a bipartite RNA-binding protein that post-transcriptionally inhibits the biogenesis of let-7 microRNAs to regulate development and influence disease states. However, the mechanisms of let-7 suppression remains poorly understood, because LIN28 recognition depends on coordinated targeting by...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6238216/ https://ncbi.nlm.nih.gov/pubmed/30029005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.029 |
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