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A single let-7 microRNA bypasses LIN28-mediated repression
Let-7 microRNAs (miRNAs) are critical regulators of animal development, stem cell differentiation, glucose metabolism, and tumorigenesis. Mammalian genomes contain twelve let-7 isoforms that suppress expression of a common set of target mRNAs. LIN28 proteins selectively block let-7 biogenesis in und...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607659/ https://ncbi.nlm.nih.gov/pubmed/26440890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.086 |
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