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Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

A hallmark of mammalian embryonic development is the widespread induction of microRNA (miRNA) expression. Surprisingly, the transcription of many of these small, noncoding RNAs is unchanged through development; rather, a post-transcriptional regulatory event prevents accumulation of the mature miRNA...

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Detalhes bibliográficos
Main Authors: Newman, Martin A., Thomson, J. Michael, Hammond, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491462/
https://ncbi.nlm.nih.gov/pubmed/18566191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1155108
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