Loading...
Inhibition of XPO1 enhances cell death induced by ABT‐199 in acute myeloid leukaemia via Mcl‐1
The antiapoptotic Bcl‐2 family proteins play critical roles in resistance to chemotherapy in acute myeloid leukaemia (AML). The Bcl‐2‐selective inhibitor ABT‐199 (Venetoclax) shows promising antileukaemic activity against AML, though Mcl‐1 limits its antileukaemic activity. XPO1 is a nuclear exporte...
Na minha lista:
| Udgivet i: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237582/ https://ncbi.nlm.nih.gov/pubmed/30596398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13886 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|