Ex vivo lung perfusion as a human platform for preclinical small molecule testing

The acute respiratory distress syndrome (ARDS) causes an estimated 70,000 US deaths annually. Multiple pharmacologic interventions for ARDS have been tested and failed. An unmet need is a suitable laboratory human model to predictively assess emerging therapeutics on organ function in ARDS. We previ...

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Publicat a:JCI Insight
Autors principals: Weathington, Nathaniel M., Álvarez, Diana, Sembrat, John, Radder, Josiah, Cárdenes, Nayra, Noda, Kentaro, Gong, Qiaoke, Wong, Hesper, Kolls, Jay, D’Cunha, Jonathan, Mallampalli, Rama K., Chen, Bill B., Rojas, Mauricio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Technical Advance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237445/
https://ncbi.nlm.nih.gov/pubmed/30282819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95515
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