Glycogen Synthase Kinase-3β Stabilizes the Interleukin (IL)-22 Receptor from Proteasomal Degradation in Murine Lung Epithelia

Signaling through the interleukin (IL)-22 cytokine axis provides essential immune protection in the setting of extracellular infection as part of type 17 immunity. Molecular regulation of IL-22 receptor (IL-22R) protein levels is unknown. In murine lung epithelia, IL-22R is a relatively short-lived...

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Hlavní autoři: Weathington, Nathaniel M., Snavely, Courtney A., Chen, Bill B., Zhao, Jing, Zhao, Yutong, Mallampalli, Rama K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Protein Synthesis and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067196/
https://ncbi.nlm.nih.gov/pubmed/24742671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551747
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