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Emerging therapies targeting the ubiquitin proteasome system in cancer
The ubiquitin proteasome system (UPS) is an essential metabolic constituent of cellular physiology that tightly regulates cellular protein concentrations with specificity and precision to optimize cellular function. Inhibition of the proteasome has proven very effective in the treatment of multiple...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871250/ https://ncbi.nlm.nih.gov/pubmed/24382383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71602 |
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