Combination anti–PD-1 and antiretroviral therapy provides therapeutic benefit against SIV

Therapeutic strategies that augment antiviral immunity and reduce the viral reservoir are critical to achieving durable remission of HIV. The coinhibitory receptor programmed death-1 (PD-1) regulates CD8(+) T cell dysfunction during chronic HIV and SIV infections. We previously demonstrated that in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Mylvaganam, Geetha H., Chea, Lynette S., Tharp, Gregory K., Hicks, Sakeenah, Velu, Vijayakumar, Iyer, Smita S., Deleage, Claire, Estes, Jacob D., Bosinger, Steven E., Freeman, Gordon J., Ahmed, Rafi, Amara, Rama R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2018
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237231/
https://ncbi.nlm.nih.gov/pubmed/30232277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122940
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