Combination anti–PD-1 and antiretroviral therapy provides therapeutic benefit against SIV

Therapeutic strategies that augment antiviral immunity and reduce the viral reservoir are critical to achieving durable remission of HIV. The coinhibitory receptor programmed death-1 (PD-1) regulates CD8(+) T cell dysfunction during chronic HIV and SIV infections. We previously demonstrated that in...

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Опубликовано в: :JCI Insight
Главные авторы: Mylvaganam, Geetha H., Chea, Lynette S., Tharp, Gregory K., Hicks, Sakeenah, Velu, Vijayakumar, Iyer, Smita S., Deleage, Claire, Estes, Jacob D., Bosinger, Steven E., Freeman, Gordon J., Ahmed, Rafi, Amara, Rama R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237231/
https://ncbi.nlm.nih.gov/pubmed/30232277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122940
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