Combination anti–PD-1 and antiretroviral therapy provides therapeutic benefit against SIV

Therapeutic strategies that augment antiviral immunity and reduce the viral reservoir are critical to achieving durable remission of HIV. The coinhibitory receptor programmed death-1 (PD-1) regulates CD8(+) T cell dysfunction during chronic HIV and SIV infections. We previously demonstrated that in...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Mylvaganam, Geetha H., Chea, Lynette S., Tharp, Gregory K., Hicks, Sakeenah, Velu, Vijayakumar, Iyer, Smita S., Deleage, Claire, Estes, Jacob D., Bosinger, Steven E., Freeman, Gordon J., Ahmed, Rafi, Amara, Rama R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237231/
https://ncbi.nlm.nih.gov/pubmed/30232277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122940
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