Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection

A significant challenge to HIV eradication is the elimination of viral reservoirs in germinal center (GC) T follicular helper (Tfh) cells. However, GCs are considered to be immune privileged for antiviral CD8 T cells. Here, we show a population of simian immunodeficiency virus (SIV)-specific CD8 T c...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mylvaganam, Geetha H., Rios, Daniel, Abdelaal, Hadia M., Iyer, Smita, Tharp, Gregory, Mavigner, Maud, Hicks, Sakeenah, Chahroudi, Ann, Ahmed, Rafi, Bosinger, Steven E., Williams, Ifor R., Skinner, Pamela J., Velu, Vijayakumar, Amara, Rama R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338410/
https://ncbi.nlm.nih.gov/pubmed/28159893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621418114
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