Induction of Th1 biased Tfh (Tfh1 cells) in lymphoid tissues during chronic SIV infection defines functionally distinct germinal center Tfh cells

Chronic HIV infection is associated with accumulation of germinal center T follicular helper cells (GC-Tfh) in the lymphoid tissue. The GC-Tfh cells can be heterogeneous based on the expression of chemokine receptors associated with T helper lineages such as CXCR3 (Th1), CCR4 (Th2), and CCR6 (Th17)....

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Publicado en:J Immunol
Main Authors: Velu, Vijayakumar, Mylvaganam, Geetha Hanna, Gangadhara, Sailaja, Hong, Jung Joo, Iyer, Smita S., Gumber, Sanjeev, Ibegbu, Chris C., Villinger, Francois, Amara, Rama Rao
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992610/
https://ncbi.nlm.nih.gov/pubmed/27481845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600143
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