Induction of Th1 biased Tfh (Tfh1 cells) in lymphoid tissues during chronic SIV infection defines functionally distinct germinal center Tfh cells

Chronic HIV infection is associated with accumulation of germinal center T follicular helper cells (GC-Tfh) in the lymphoid tissue. The GC-Tfh cells can be heterogeneous based on the expression of chemokine receptors associated with T helper lineages such as CXCR3 (Th1), CCR4 (Th2), and CCR6 (Th17)....

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Velu, Vijayakumar, Mylvaganam, Geetha Hanna, Gangadhara, Sailaja, Hong, Jung Joo, Iyer, Smita S., Gumber, Sanjeev, Ibegbu, Chris C., Villinger, Francois, Amara, Rama Rao
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992610/
https://ncbi.nlm.nih.gov/pubmed/27481845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600143
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items