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Diminished Viral Control during SIV Infection is Associated with Aberrant PD-1(hi) CD4 T cell Enrichment in the Lymphoid Follicles of the Rectal Mucosa
The inhibitory receptor Programmed Death-1 (PD-1) has been shown to regulate CD8 T cell function during chronic SIV infection, however its role on CD4 T cells, specifically in the gut associated lymphoid tissue, is less well understood. Here, we show that a subset of CD4 T cells express high levels...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201952/ https://ncbi.nlm.nih.gov/pubmed/25246494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401222 |
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