CD40L-Adjuvanted DNA/Modified Vaccinia Virus Ankara Simian Immunodeficiency Virus (SIV) Vaccine Enhances Protection against Neutralization-Resistant Mucosal SIV Infection

Here, we show that a CD40L-adjuvanted DNA/modified vaccinia virus Ankara (MVA) simian immunodeficiency virus (SIV) vaccine enhances protection against a pathogenic neutralization-resistant mucosal SIV infection, improves long-term viral control, and prevents AIDS. Analyses of serum IgG antibodies to...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Kwa, Suefen, Sadagopal, Shanmugalakshmi, Shen, Xiaoying, Hong, Jung Joo, Gangadhara, Sailaja, Basu, Rahul, Victor, Blandine, Iyer, Smita S., LaBranche, Celia C., Montefiori, David C., Tomaras, Georgia D., Villinger, Francois, Moss, Bernard, Kozlowski, Pamela A., Amara, Rama Rao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442387/
https://ncbi.nlm.nih.gov/pubmed/25653428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03527-14
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