CD40L-Adjuvanted DNA/Modified Vaccinia Virus Ankara Simian Immunodeficiency Virus (SIV) Vaccine Enhances Protection against Neutralization-Resistant Mucosal SIV Infection

Here, we show that a CD40L-adjuvanted DNA/modified vaccinia virus Ankara (MVA) simian immunodeficiency virus (SIV) vaccine enhances protection against a pathogenic neutralization-resistant mucosal SIV infection, improves long-term viral control, and prevents AIDS. Analyses of serum IgG antibodies to...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kwa, Suefen, Sadagopal, Shanmugalakshmi, Shen, Xiaoying, Hong, Jung Joo, Gangadhara, Sailaja, Basu, Rahul, Victor, Blandine, Iyer, Smita S., LaBranche, Celia C., Montefiori, David C., Tomaras, Georgia D., Villinger, Francois, Moss, Bernard, Kozlowski, Pamela A., Amara, Rama Rao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442387/
https://ncbi.nlm.nih.gov/pubmed/25653428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03527-14
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