Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection

A significant challenge to HIV eradication is the elimination of viral reservoirs in germinal center (GC) T follicular helper (Tfh) cells. However, GCs are considered to be immune privileged for antiviral CD8 T cells. Here, we show a population of simian immunodeficiency virus (SIV)-specific CD8 T c...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Mylvaganam, Geetha H., Rios, Daniel, Abdelaal, Hadia M., Iyer, Smita, Tharp, Gregory, Mavigner, Maud, Hicks, Sakeenah, Chahroudi, Ann, Ahmed, Rafi, Bosinger, Steven E., Williams, Ifor R., Skinner, Pamela J., Velu, Vijayakumar, Amara, Rama R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338410/
https://ncbi.nlm.nih.gov/pubmed/28159893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621418114
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