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Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress

Ferroportin (FPN), the only known vertebrate iron exporter, transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues and cells in vivo. Most of the circulating iron is consumed by erythroid cells to synthesize hemoglobin. Here we found that erythroi...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Zhang, De-Liang, Ghosh, Manik C., Ollivierre, Hayden, Li, Yan, Rouault, Tracey A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236465/
https://ncbi.nlm.nih.gov/pubmed/30213870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-04-842997
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