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Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress
Ferroportin (FPN), the only known vertebrate iron exporter, transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues and cells in vivo. Most of the circulating iron is consumed by erythroid cells to synthesize hemoglobin. Here we found that erythroi...
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| Publicado en: | Blood |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6236465/ https://ncbi.nlm.nih.gov/pubmed/30213870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-04-842997 |
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