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Filter Retardation Assay for Detecting and Quantifying Polyglutamine Aggregates Using Caenorhabditis elegans Lysates

Protein aggregation is a hallmark of several neurodegenerative diseases and is associated with impaired protein homeostasis. This imbalance is caused by the loss of the protein’s native conformation, which ultimately results in its aggregation or abnormal localization within the cell. Using a C. ele...

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Detaylı Bibliyografya
Yayımlandı:Bio Protoc
Asıl Yazarlar: Sin, Olga, Mata-Cabana, Alejandro, Seinstra, Renée I., Nollen, Ellen A. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Bio-Protocol 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235101/
https://ncbi.nlm.nih.gov/pubmed/30450365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3042
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