Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans

The nematode worm Caenorhabditis elegans has emerged as an important model organism in the study of the molecular mechanisms of protein misfolding diseases associated with amyloid formation because of its small size, ease of genetic manipulation, and optical transparency. Obtaining a reliable and qu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Biol
Prif Awduron: Laine, Romain F., Sinnige, Tessa, Ma, Kai Yu, Haack, Amanda J., Poudel, Chetan, Gaida, Peter, Curry, Nathan, Perni, Michele, Nollen, Ellen A.A., Dobson, Christopher M., Vendruscolo, Michele, Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612977/
https://ncbi.nlm.nih.gov/pubmed/31246415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00354
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