HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

BACKGROUND: In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments. Hypoxia-inducible factors (HIFs) regulate gene transcripti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Skelet Muscle
Egile Nagusiak: Billin, Andrew N., Honeycutt, Samuel E., McDougal, Alan V., Kerr, Jaclyn P., Chen, Zhe, Freudenberg, Johannes M., Rajpal, Deepak K., Luo, Guizhen, Kramer, Henning Fritz, Geske, Robert S., Fang, Frank, Yao, Bert, Clark, Richard V., Lepore, John, Cobitz, Alex, Miller, Ram, Nosaka, Kazunori, Hinken, Aaron C., Russell, Alan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234580/
https://ncbi.nlm.nih.gov/pubmed/30424786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0179-5
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