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The role of HIF prolyl hydroxylases in tumour growth

Tumour hypoxia is a well-known microenvironmental factor that causes cancer progression and resistance to cancer treatment. This involves multiple mechanisms of which the best-understood ones are mediated through transcriptional gene activation by the hypoxia-inducible factors (HIFs). HIFs in turn a...

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Hlavní autoři: Jokilehto, Terhi, Jaakkola, Panu M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823110/
https://ncbi.nlm.nih.gov/pubmed/20178464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01030.x
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