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The role of HIF prolyl hydroxylases in tumour growth

Tumour hypoxia is a well-known microenvironmental factor that causes cancer progression and resistance to cancer treatment. This involves multiple mechanisms of which the best-understood ones are mediated through transcriptional gene activation by the hypoxia-inducible factors (HIFs). HIFs in turn a...

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Detalhes bibliográficos
Main Authors: Jokilehto, Terhi, Jaakkola, Panu M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823110/
https://ncbi.nlm.nih.gov/pubmed/20178464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01030.x
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