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Prolyl Hydroxylase PHD3 Enhances the Hypoxic Survival and G1 to S Transition of Carcinoma Cells

Hypoxia restricts cell proliferation and cell cycle progression at the G1/S interface but at least a subpopulation of carcinoma cells can escape the restriction. In carcinoma hypoxia may in fact select for cells with enhanced hypoxic survival and increased aggressiveness. The cellular oxygen sensors...

詳細記述

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書誌詳細
主要な著者: Högel, Heidi, Rantanen, Krista, Jokilehto, Terhi, Grenman, Reidar, Jaakkola, Panu M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210766/
https://ncbi.nlm.nih.gov/pubmed/22087251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027112
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