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Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation
The HIF prolyl hydroxylases (PHDs/EGLNs) are central regulators of the molecular responses to oxygen availability. One isoform, PHD3, is expressed in response to hypoxia and causes apoptosis in oxygenated conditions in neural cells. Here we show that PHD3 forms subcellular aggregates in an oxygen-de...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366864/ https://ncbi.nlm.nih.gov/pubmed/18337469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-11-1124 |
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