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Stereoselective Synthesis of Dihydroisocoumarin Moiety of Microbial Agent AI-77-B: a Diels-Alder Based Strategy

The dihydroisocoumarin fragment of the gastroprotective natural product AI-77-B has been synthesized in optically active form by using a regiospecific Diels-Alder reaction of 1-methoxy-1,3-cyclohexadiene and an acetylenic ester derivative, prepared stereoselectively from leucinal.

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Bibliografiske detaljer
Udgivet i:Tetrahedron Lett
Main Authors: Ghosh, Arun K., Cappiello, John
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226092/
https://ncbi.nlm.nih.gov/pubmed/30422131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(98)01977-7
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