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Asymmetric Total Synthesis of the Gastroprotective Microbial Agent AI-77-B

An enantioselective total synthesis of the pseudopeptide microbial agent AI-77-B, which has shown potent antiulcerogenic properties, is described. The synthesis is convergent and involves the assembly of a dihydroisocoumarin fragment and a hydroxy amino acid. The dihydroisocoumarin derivative was sy...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Ghosh, Arun K., Bischoff, Alexander, Cappiello, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214212/
https://ncbi.nlm.nih.gov/pubmed/30393460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.200390125
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