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Asymmetric Total Synthesis of (+)-Merobatzelladine B

The first total synthesis of (+)-merobatzelladine B was accomplished using an iterative sequence of stereoselective Pd-catalyzed alkene carboamination reactions for formation of two of the three rings. This represents a new strategy for the generation of polycyclic guanidine natural products, and pr...

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Bibliographic Details
Main Authors: Babij, Nicholas R., Wolfe, John P.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481174/
https://ncbi.nlm.nih.gov/pubmed/22431071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201201001
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