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Asymmetric hetero Diels-Alder route to quaternary carbon centers: synthesis of (−)-malyngolide

Conformationally constrained chiral bis(oxazoline)-metal complex catalyzed asymmetric hetero Diels-Alder reactions of Danishefsky’s diene and a variety of α-keto esters constructed quaternary carbon centers enantioselectively. The reaction was utilized in the synthesis of (−)-malyngolide.

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Bibliografiske detaljer
Udgivet i:Tetrahedron Lett
Main Authors: Ghosh, Arun K., Shirai, Michio
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214206/
https://ncbi.nlm.nih.gov/pubmed/30393409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0040-4039(01)01227-8
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